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When Retinoids Visit the Skin

By Nat Habit

Day of Synthetic Retinol

(Lab-made, highly active, and ready to rewrite everything)

Keratinocyte (skin cell, surprised):

“Wait—who is this? She’s strong, no buffering, straight to my DNA?” “She’s flipping my collagen genes on and pushing me to divide faster. I’m exfoliating from the inside out!”

Corneocyte (surface skin tile, overwhelmed):

“I'm not ready yet! I just got here and now I’m flaking off?” “No time to mature. No lipids formed. No barrier built.” “This is shedding, not renewal!”

Langerhans Cell (immune guard, stressed):

“This molecule is known for triggering inflammation. Barrier's thinning. Redness rising. Should I send in cytokines?”

Microbiome (fading):

“Ugh
 it’s dry, acidic, stripped. We’re losing friendly species. This isn’t exfoliation—it’s eviction.”

Fibroblast (collagen maker, cautiously working):

“She tells me to build more collagen—but if inflammation stays high, I’ll have to pause and just protect what’s left.”

Melanocyte (on alert):

“If redness or irritation escalates, I’m going to have to step in with melanin to shield the area.” “Don’t be surprised if post-inflammatory pigmentation shows up.”

Skin’s Whisper:

“Retinol is powerful—but power without protection causes panic. I glow
 but I ache.”

Day of Natural Vitamin A

(Bakuchiol, Carrot Seed Oil, Rosehip—gentle nudgers, not pushers)

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Keratinocyte (calm and curious):

“Ah, here comes Bakuchiol. She’s like Retinol’s softer twin.” “She doesn’t barge in. She suggests—‘Hey, maybe make more collagen?’” “No stinging, no peeling, just gradual renewal.”

Corneocyte (peaceful):

“I’m allowed to mature! I formed my lipids, sealed the barrier, and now I’m ready to shed—gracefully.” “This is what healthy turnover feels like.”

Langerhans Cell (relaxed):

“Nothing alarming here. Antioxidants, calming phytonutrients, and no red flags. This isn’t war—it’s wellness.”

Microbiome (thriving):

“Oh yes! Rosehip oil? Carrot seed? These are our favourite dishes. We’re balanced, well-fed, and multiplying beautifully.”

Fibroblast (gently encouraged):

“I’m receiving a soft but steady nudge to build collagen. No stress signals, just growth mode.”

Melanocyte (content):

“No inflammation, no need for extra melanin. Skin tone stays even, protected from pigment rebound.”

Skin’s Smile:

“She may be slower—but she’s kind. Natural vitamin A gives me time, nourishment, and lasting radiance.”

Skin’s Final Thought:

“Retinol pushes. Bakuchiol persuades.
One demands glow. The other nurtures it.”

“Support me, buffer me, and I’ll shine either way—but if you want beauty with peace, go gentle.”

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